Scleroderma, collagen or vascular diseases,
blood clotting conditions,
active bacterial or fungal infections,
pregnancy, breast feeding, keloid scars,
psoriasis and other chronic skin conditions.
History of actinic or solar keratosis, history of herpes simplex infections, history of diabetes. Overactive acne, rosacea, or other inflammatory skin conditions. 6 months after the use of Accutane.